This is a ready-to-frame Giclée art print of the Serenity Prayer in Japanese Kanji and Hiragana characters.
This is a Japanese version of the Serenity Prayer, as used by many 12-step programs and support groups.
In Japanese, this says:
God grant me the serenity to accept the things I cannot change, the courage to change the things I can, and the wisdom to know the difference. In this Japanese version, "God" is translated as "Spirit" which can be any diety in which you have faith.
If you want to try to pronounce it, this romanizes as:
Kamisama ha watashi ni kaeru koto no deki nai mono o ukeireru odayaka sa to kaeru koto no dekiru yuuki to sono chigai o shiru kenmei sa o ataeru.